Gut Dysbiosis and Mitochondrial Dysfunction in Autism Spectrum Disorder

  • 26 Mar 2019
  • 6:00 PM - 8:00 PM
  • Autism Connection of PA, 35 Wilson Street, Suite 101, Pittsburgh, PA 15223
  • 32

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Gut Dysbiosis and Mitochondrial Dysfunction in Autism Spectrum Disorder

 Presented by:

Sri Ganeshan, MD
Chief Medical Officer, ReligenDX Inc.


Tuesday, March 26, 2019

6:00 p.m. – 8:00 p.m. 


**Social Worker and Act 48 credits available**


Dr. Ganeshan and his colleagues are involved in understanding the role of mitochondria and microbiome in human disease. He will present on the microorganisms living in the gut (gastrointestinal system) and how they play a critical role in our day to day function when they are balanced (balance of good microbe’s vs the bad). If this balance is altered in the gut (dysbiosis) this can affect many other parts of the body through the chemicals, hormones, and other mechanisms. One such part of the body which is affected is the brain. The gut communicates with the brain through pathways including the nerves, hormones, altering the immune system etc.

These effects can be detrimental to a growing child and may present as behavioral symptoms. Some of these substances made by the microorganisms affect the mitochondria, which are the energy source for our body function. The mitochondria may be affected by many factors including the environment, genetics, infection, stress etc. Dysfunctional mitochondria may play a role in autism.

The talk will focus on the mitochondria microbiome connection and the crosstalk in autism. Challenges and opportunities to modify them for a better quality of life for children with autism.

At the completion of this session, learners will be able to:

  • Microbiota and dysbiosis in Autism Spectrum Disorder (ASD)
  • What is the microbiome? Why is it important to learn more about it in autism?
  • Mitochondrial Dysfunction in Autism Spectrum Disorder
  • What are the mitochondria? It’s importance in human disease
  • Gut- Brain Axis in Autism Spectrum disorder: How the changes in the gastrointestinal system effect the brain in children with autism.

ABOARD's Autism Connection of PA    35 Wilson Street     Pittsburgh, PA 15223     (412) 781-4116         The Commonwealth of Pennsylvania certifies that the Advisory Board On Autism and Related Disorders is registered as a charitable organization with the Department of State's Bureau of Charitable Organizations under the Solicitation of Funds for Charitable Purposes Acts, 10 P.S. Section 161.2 et seq., and is authorized to solicit charitable contributions under the conditions and limitations set forth under the Act. The certification does not imply endorsement by the Commonwealth. 
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